Differentiation of zebrafish melanophores depends on transcription factors AP2 alpha and AP2 epsilon

A model of the gene-regulatory-network (GRN), governing growth, survival, and differentiation of melanocytes, has emerged from studies of mouse coat color mutants and melanoma cell lines. In this model, Transcription Factor Activator Protein 2 alpha (TFAP2A) contributes to melanocyte development by...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS genetics 2010-09, Vol.6 (9), p.e1001122-e1001122
Hauptverfasser:	Van Otterloo, Eric, Li, Wei, Bonde, Gregory, Day, Kristopher M, Hsu, Mei-Yu, Cornell, Robert A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Death Cell Differentiation Cell Lineage Cells, Cultured Chromatophores (Zoology) Cyclin-dependent kinases Danio rerio Developmental Biology Embryo, Nonmammalian - cytology Embryo, Nonmammalian - metabolism Embryonic development Embryos Experiments Freshwater Gene expression Gene Expression Regulation, Developmental Genes Genetic aspects Genetics and Genomics Growth Humans Kinases Ligands Melanocytes - cytology Melanocytes - metabolism Melanophores - cytology Melanophores - metabolism Mice Microphthalmia-Associated Transcription Factor - genetics Migration Models, Biological Mutation - genetics Organ Specificity - genetics Phosphorylation Physiological aspects Proteins Proto-Oncogene Proteins c-kit - metabolism Signal transduction Studies Transcription Factor AP-2 - genetics Transcription Factor AP-2 - metabolism Transcription Factors - genetics Transcription Factors - metabolism Transcriptional Activation - genetics Zebra fish Zebrafish Zebrafish - embryology Zebrafish - genetics Zebrafish - metabolism Zebrafish Proteins - genetics Zebrafish Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!