Nodal-dependent mesendoderm specification requires the combinatorial activities of FoxH1 and Eomesodermin

Vertebrate mesendoderm specification requires the Nodal signaling pathway and its transcriptional effector FoxH1. However, loss of FoxH1 in several species does not reliably cause the full range of loss-of-Nodal phenotypes, indicating that Nodal signals through additional transcription factors durin...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS genetics 2011-05, Vol.7 (5), p.e1002072-e1002072
Hauptverfasser:	Slagle, Christopher E, Aoki, Tsutomu, Burdine, Rebecca D
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Biology Body Patterning Cellular signal transduction Chromosome Mapping Defects Embryo, Nonmammalian - embryology Embryo, Nonmammalian - metabolism Embryos Epistasis, Genetic Evacuations & rescues Experiments Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism Gene expression Gene Expression Regulation, Developmental Gene Knockdown Techniques Genetic aspects Genetic transcription Genotype Growth Homeodomain Proteins - metabolism Mesoderm Mesoderm - embryology Mutation Notochord - embryology Notochord - metabolism Phenotype Physiological aspects Proteins Signal Transduction T-Box Domain Proteins - metabolism Transcription Factors - metabolism Vertebrates Zebrafish - embryology Zebrafish - genetics Zebrafish - metabolism Zebrafish Proteins - genetics Zebrafish Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!