Genetic variants at chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 influence the risk of breast cancer in men

Male breast cancer accounts for approximately 1% of all breast cancer. To date, risk factors for male breast cancer are poorly defined, but certain risk factors and genetic features appear common to both male and female breast cancer. Genome-wide association studies (GWAS) have recently identified c...

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Veröffentlicht in:	PLoS genetics 2011-09, Vol.7 (9), p.e1002290-e1002290
Hauptverfasser:	Orr, Nick, Cooke, Rosie, Jones, Michael, Fletcher, Olivia, Dudbridge, Frank, Chilcott-Burns, Sarah, Tomczyk, Katarzyna, Broderick, Peter, Houlston, Richard, Ashworth, Alan, Swerdlow, Anthony
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Apoptosis Regulatory Proteins Biology BRCA mutations Breast cancer Breast Neoplasms - genetics Breast Neoplasms, Male - genetics Case-Control Studies Chromosomes, Human - genetics Chromosomes, Human, Pair 10 - genetics Chromosomes, Human, Pair 16 - genetics Chromosomes, Human, Pair 2 - genetics Chromosomes, Human, Pair 5 - genetics Chromosomes, Human, Pair 6 - genetics Copper Transport Proteins Electron Transport Chain Complex Proteins Electron Transport Complex IV - genetics Female Genetic aspects Genetic Association Studies Genetic Predisposition to Disease Genetic Variation Genotype Health aspects High Mobility Group Proteins Humans Male Medical research Medicine Men Middle Aged Mitochondrial Proteins Odds Ratio Polymorphism, Single Nucleotide Receptors, Progesterone - genetics Risk Factors Single nucleotide polymorphisms Therapy Trans-Activators Whites Women Young Adult
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