The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny

Methylation of histone H3K36 in higher eukaryotes is mediated by multiple methyltransferases. Set2-related H3K36 methyltransferases are targeted to genes by association with RNA Polymerase II and are involved in preventing aberrant transcription initiation within the body of genes. The targeting and...

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Veröffentlicht in:	PLoS genetics 2010-09, Vol.6 (9), p.e1001091-e1001091
Hauptverfasser:	Rechtsteiner, Andreas, Ercan, Sevinc, Takasaki, Teruaki, Phippen, Taryn M, Egelhofer, Thea A, Wang, Wenchao, Kimura, Hiroshi, Lieb, Jason D, Strome, Susan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites Biocatalysis Caenorhabditis elegans Caenorhabditis elegans - embryology Caenorhabditis elegans - enzymology Caenorhabditis elegans - genetics Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Deoxyribonucleic acid Developmental Biology Developmental Biology/Developmental Molecular Mechanisms Developmental Biology/Germ Cells DNA DNA methylation Embryo, Nonmammalian - cytology Embryo, Nonmammalian - enzymology Embryonic development Embryos Epigenesis, Genetic Epigenetic inheritance Epigenetics Female Gene expression Gene Expression Regulation, Developmental Genes, Helminth - genetics Genetic aspects Genetics Genetics and Genomics Genetics and Genomics/Chromosome Biology Genetics and Genomics/Epigenetics Genetics and Genomics/Genome Projects Genomes Germ Cells - cytology Germ Cells - enzymology Histone-Lysine N-Methyltransferase - metabolism Histones Histones - metabolism Lysine - metabolism Methylation Methyltransferases Open Reading Frames - genetics Physiological aspects Properties Protein Binding Proteins RNA Interference RNA polymerase RNA Polymerase II - metabolism X Chromosome - metabolism
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