Controls of nucleosome positioning in the human genome

Nucleosomes are important for gene regulation because their arrangement on the genome can control which proteins bind to DNA. Currently, few human nucleosomes are thought to be consistently positioned across cells; however, this has been difficult to assess due to the limited resolution of existing...

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Veröffentlicht in:	PLoS genetics 2012-11, Vol.8 (11), p.e1003036-e1003036
Hauptverfasser:	Gaffney, Daniel J, McVicker, Graham, Pai, Athma A, Fondufe-Mittendorf, Yvonne N, Lewellen, Noah, Michelini, Katelyn, Widom, Jonathan, Gilad, Yoav, Pritchard, Jonathan K
Format:	Artikel
Sprache:	eng
Schlagworte:	Arrays Bias Biology Cell Line Chromatin - genetics Chromatin Assembly and Disassembly - genetics Deoxyribonuclease I - genetics Deoxyribonuclease I - metabolism Deoxyribonucleic acid DNA DNA - genetics DNA-Binding Proteins Genome, Human Genomes Genomics Health aspects Human genetics Humans Micrococcal Nuclease - metabolism Nucleosomes Nucleosomes - genetics Physiological aspects Promoter Regions, Genetic Proteins Sequence Analysis, DNA
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