Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis

Recent studies indicate a mutual epidemiological relationship between coronary heart disease (CHD) and periodontitis. Both diseases are associated with similar risk factors and are characterized by a chronic inflammatory process. In a candidate-gene association study, we identify an association of a...

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Veröffentlicht in:	PLoS genetics 2009-02, Vol.5 (2), p.e1000378-e1000378
Hauptverfasser:	Schaefer, Arne S, Richter, Gesa M, Groessner-Schreiber, Birte, Noack, Barbara, Nothnagel, Michael, El Mokhtari, Nour-Eddine, Loos, Bruno G, Jepsen, Søren, Schreiber, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cardiovascular disease Chromosomes, Human, Pair 9 - genetics Confidence intervals Coronary Disease - genetics Coronary heart disease Cyclin-Dependent Kinase Inhibitor p15 - genetics Cyclin-Dependent Kinase Inhibitor p16 - genetics Diabetes Diabetes Mellitus, Type 2 - genetics Female Genetic aspects Genetic Predisposition to Disease Genetic susceptibility Genetics Genetics and Genomics/Gene Discovery Genetics and Genomics/Genetics of Disease Genetics and Genomics/Genetics of the Immune System Genetics and Genomics/Medical Genetics Genomes Genotype Germany Health risk assessment Heart Humans Immunology/Genetics of the Immune System Linkage Disequilibrium Male Middle Aged Periodontitis Periodontitis - genetics Polymorphism, Single Nucleotide Risk factors RNA, Antisense - genetics Single nucleotide polymorphisms
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