LINE retrotransposon RNA is an essential structural and functional epigenetic component of a core neocentromeric chromatin

We have previously identified and characterized the phenomenon of ectopic human centromeres, known as neocentromeres. Human neocentromeres form epigenetically at euchromatic chromosomal sites and are structurally and functionally similar to normal human centromeres. Recent studies have indicated tha...

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Veröffentlicht in:	PLoS genetics 2009-01, Vol.5 (1), p.e1000354-e1000354
Hauptverfasser:	Chueh, Anderly C, Northrop, Emma L, Brettingham-Moore, Kate H, Choo, K H Andy, Wong, Lee H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoantigens - genetics Autoantigens - metabolism Cell division Cell Line Centromere - chemistry Centromere - genetics Centromere - metabolism Centromere Protein A Centromeres Chromatin Chromatin - chemistry Chromatin - metabolism Chromosomal Proteins, Non-Histone - genetics Chromosomal Proteins, Non-Histone - metabolism Chromosomes Chromosomes, Human, Pair 10 - genetics Cricetinae Deoxyribonucleic acid DNA DNA methylation Epigenesis, Genetic Epigenetics Experiments Genetics and Genomics/Chromosome Biology Genomes Humans Long Interspersed Nucleotide Elements Mice Mitosis Molecular Biology/Centromeres Molecular Biology/Chromatin Structure Physiological aspects Retrotransposons RNA - genetics RNA - metabolism Transcription, Genetic
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