The next generation becomes the now generation

  Interestingly, this is similar to the blend of long- and short-insert libraries that were used for the whole genome shotgun version of the human genome project [6]. [...]the authors used polymerase chain reaction (PCR) to amplify across the boundaries of the inverted and duplicated region, and end...

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Veröffentlicht in:PLoS genetics 2010-04, Vol.6 (4), p.e1000906-e1000906
Hauptverfasser: Martinez, Diego A, Nelson, Mary Anne
Format: Artikel
Sprache:eng
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Zusammenfassung:  Interestingly, this is similar to the blend of long- and short-insert libraries that were used for the whole genome shotgun version of the human genome project [6]. [...]the authors used polymerase chain reaction (PCR) to amplify across the boundaries of the inverted and duplicated region, and end-sequenced the PCR products to confirm the genome structure predicted by the genome assembler Velvet [7].
ISSN:1553-7404
1553-7390
1553-7404
DOI:10.1371/journal.pgen.1000906