Y chromosome lineage- and village-specific genes on chromosomes 1p22 and 6q27 control visceral leishmaniasis in Sudan

Familial clustering and ethnic differences suggest that visceral leishmaniasis caused by Leishmania donovani is under genetic control. A recent genome scan provided evidence for a major susceptibility gene on Chromosome 22q12 in the Aringa ethnic group in Sudan. We now report a genome-wide scan usin...

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Veröffentlicht in:	PLoS genetics 2007-05, Vol.3 (5), p.e71-e71
Hauptverfasser:	Miller, E Nancy, Fadl, Manal, Mohamed, Hiba S, Elzein, Abier, Jamieson, Sarra E, Cordell, Heather J, Peacock, Christopher S, Fakiola, Michaela, Raju, Madhuri, Khalil, Eltahir A, Elhassan, Ahmed, Musa, Ahmed M, Ibrahim, Muntaser E, Blackwell, Jenefer M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Alleles Child Child, Preschool Chromosome Mapping Chromosomes Chromosomes, Human, Pair 1 - genetics Chromosomes, Human, Pair 6 - genetics Chromosomes, Human, Y - genetics Consanguinity Control DNA, Mitochondrial - genetics Female Genes Genetic aspects Genetics Genetics and Genomics Genome, Human - genetics Genomics Haplotypes Health aspects Homo (Human) Humans Kala-azar Leishmaniasis, Visceral - genetics Lod Score Male Microsatellite Repeats - genetics Molecular Sequence Data Parasitic diseases Pedigree Rural Health Rural Population Social aspects Species Specificity Sudan Y chromosome
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