Network archaeology: uncovering ancient networks from present-day interactions

What proteins interacted in a long-extinct ancestor of yeast? How have different members of a protein complex assembled together over time? Our ability to answer such questions has been limited by the unavailability of ancestral protein-protein interaction (PPI) networks. To overcome this limitation...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS computational biology 2011-04, Vol.7 (4), p.e1001119
Hauptverfasser:	Navlakha, Saket, Kingsford, Carl
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Animals Cluster Analysis Computational Biology - methods Computational Biology/Systems Biology Computer Science Computer Simulation Endangered & extinct species Evolution, Molecular Fungal Proteins - metabolism Gene Deletion Genes, Fungal Methods Models, Theoretical Molecular Biology/Bioinformatics Phylogenetics Probability Protein Interaction Mapping - methods Protein research Protein-protein interactions Reproducibility of Results Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Social networks Time Factors Trees Yeast
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!