Self-organization of muscle cell structure and function

The organization of muscle is the product of functional adaptation over several length scales spanning from the sarcomere to the muscle bundle. One possible strategy for solving this multiscale coupling problem is to physically constrain the muscle cells in microenvironments that potentiate the orga...

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Veröffentlicht in:	PLoS computational biology 2011-02, Vol.7 (2), p.e1001088-e1001088
Hauptverfasser:	Grosberg, Anna, Kuo, Po-Ling, Guo, Chin-Lin, Geisse, Nicholas A, Bray, Mark-Anthony, Adams, William J, Sheehy, Sean P, Parker, Kevin Kit
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals Architectural engineering Biophysics/Cell Signaling and Trafficking Structures Biophysics/Experimental Biophysical Methods Boundary conditions Cardiomyocytes Cell Biology/Cell Adhesion Cell Biology/Cytoskeleton Cell Biology/Extra-Cellular Matrix Cell culture Cells, Cultured Computer Simulation Cytoskeleton Cytoskeleton - metabolism Cytoskeleton - physiology Experiments Focal Adhesions - chemistry Focal Adhesions - physiology Immunohistochemistry Mathematics Models, Biological Muscle cells Muscle Contraction - physiology Muscular system Myocytes, Cardiac - cytology Myocytes, Cardiac - metabolism Myocytes, Cardiac - physiology Myofibrils - chemistry Myofibrils - metabolism Myofibrils - physiology Physiology/Cardiovascular Physiology and Circulation Physiology/Morphogenesis and Cell Biology Physiology/Muscle and Connective Tissue Physiology/Pattern Formation Proteins Rats Rats, Sprague-Dawley Sarcomeres - metabolism Sarcomeres - physiology Structure Studies Symmetry
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