Deconvolution of the cellular force-generating subsystems that govern cytokinesis furrow ingression

Cytokinesis occurs through the coordinated action of several biochemically-mediated stresses acting on the cytoskeleton. Here, we develop a computational model of cellular mechanics, and using a large number of experimentally measured biophysical parameters, we simulate cell division under a number...

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Veröffentlicht in:PLoS computational biology 2012-04, Vol.8 (4), p.e1002467-e1002467
Hauptverfasser: Poirier, Christopher C, Ng, Win Pin, Robinson, Douglas N, Iglesias, Pablo A
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Sprache:eng
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