MicroRNA expression patterns and function in endodermal differentiation of human embryonic stem cells

microRNAs (miRNAs) are small noncoding RNAs that regulate cognate mRNAs post-transcriptionally. Human embryonic stem cells (hESC), which exhibit the characteristics of pluripotency and self-renewal, may serve as a model to study the role of miRNAs in early human development. We aimed to determine wh...

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Veröffentlicht in:	PloS one 2008-11, Vol.3 (11), p.e3726-e3726
Hauptverfasser:	Tzur, Galit, Levy, Asaf, Meiri, Eti, Barad, Omer, Spector, Yael, Bentwich, Zvi, Mizrahi, Lina, Katzenellenbogen, Mark, Ben-Shushan, Etti, Reubinoff, Benjamin E, Galun, Eithan
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis Cell Differentiation Cell Line Cell lines Cell self-renewal Cloning Differentiation DNA microarrays Embryo cells Embryonic stem cells Embryonic Stem Cells - cytology Embryos Endoderm Endoderm - metabolism Experiments Flow Cytometry Gastroenterology and Hepatology Gastroenterology and Hepatology/Hepatology Gene expression Gene Expression Profiling Gene therapy Genes Genetic Vectors Genetics and Genomics/Gene Therapy Genome, Human Genomes Genomics Humans Liver Metabolism MicroRNA MicroRNAs MicroRNAs - genetics miRNA Morphogenesis Oligonucleotide Array Sequence Analysis Pluripotency Polymerase chain reaction Post-transcription Reverse Transcriptase Polymerase Chain Reaction Ribonucleic acid RNA RNA polymerase Signal transduction Sodium Oxybate - pharmacology Stem cells Transcription Transcription (Genetics) Transcription Factors - metabolism
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