Contribution of Panton-Valentine leukocidin in community-associated methicillin-resistant Staphylococcus aureus pathogenesis

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strains typically carry genes encoding Panton-Valentine leukocidin (PVL). We used wild-type parental and isogenic PVL-deletion (Delta pvl) strains of USA300 (LAC and SF8300) and USA400 (MW2) to test whether PVL alters global...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2008-09, Vol.3 (9), p.e3198
Hauptverfasser:	Diep, Binh An, Palazzolo-Ballance, Amy M, Tattevin, Pierre, Basuino, Li, Braughton, Kevin R, Whitney, Adeline R, Chen, Liang, Kreiswirth, Barry N, Otto, Michael, DeLeo, Frank R, Chambers, Henry F
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animal species Animals Bacteremia Bacteremia - diagnosis Bacteremia - metabolism Bacteria Bacterial Toxins - metabolism Communities Cytokines Dentistry Disease Models, Animal DNA microarrays Drug resistance Exotoxins - metabolism Experimental infection Gene Deletion Gene expression Gene Expression Profiling Gene Expression Regulation, Bacterial Granulocytes Granulocytes - cytology Hospitals Infectious diseases Infectious Diseases/Bacterial Infections Kidneys Laboratories Leukocidin Leukocidins - metabolism Leukocytes (granulocytic) Medical research Medicine Methicillin Methicillin Resistance - drug effects Methicillin Resistance - genetics Microbial drug resistance Microbiology Neutrophils Oligonucleotide Array Sequence Analysis Pathogenesis Pneumonia Protein seeding Proteins Proteomics - methods Public health Public Health and Epidemiology/Infectious Diseases Rabbits Reverse Transcriptase Polymerase Chain Reaction Sepsis Staphylococcal infections Staphylococcus aureus Staphylococcus aureus - metabolism Staphylococcus aureus - pathogenicity Staphylococcus infections Strains (organisms) Virulence Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!