Sensing and integration of Erk and PI3K signals by Myc

The transcription factor Myc plays a central role in regulating cell-fate decisions, including proliferation, growth, and apoptosis. To maintain a normal cell physiology, it is critical that the control of Myc dynamics is precisely orchestrated. Recent studies suggest that such control of Myc can be...

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Veröffentlicht in:PLoS computational biology 2008-02, Vol.4 (2), p.e1000013-e1000013
Hauptverfasser: Lee, Tae, Yao, Guang, Nevins, Joseph, You, Lingchong
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Sprache:eng
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