Susceptibility to superhelically driven DNA duplex destabilization: a highly conserved property of yeast replication origins

Strand separation is obligatory for several DNA functions, including replication. However, local DNA properties such as A+T content or thermodynamic stability alone do not determine the susceptibility to this transition in vivo. Rather, superhelical stresses provide long-range coupling among the tra...

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Veröffentlicht in:	PLoS computational biology 2005-06, Vol.1 (1), p.e7-e7
Hauptverfasser:	Ak, Prashanth, Benham, Craig J
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics - Computational Biology Deoxyribonucleic acid DNA Eukaryotes Experiments Gene expression Genetics Genetics/Functional Genomics Genetics/Genomics Genomes Molecular Biology - Structural Biology Proteins Saccharomyces Saccharomyces cerevisiae Yeast
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