Oncologic trogocytosis of an original stromal cells induces chemoresistance of ovarian tumours

The microenvironment plays a major role in the onset and progression of metastasis. Epithelial ovarian cancer (EOC) tends to metastasize to the peritoneal cavity where interactions within the microenvironment might lead to chemoresistance. Mesothelial cells are important actors of the peritoneal hom...

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Veröffentlicht in:	PloS one 2008-12, Vol.3 (12), p.e3894
Hauptverfasser:	Rafii, Arash, Mirshahi, Pejman, Poupot, Mary, Faussat, Anne-Marie, Simon, Anne, Ducros, Elodie, Mery, Eliane, Couderc, Bettina, Lis, Raphael, Capdet, Jerome, Bergalet, Julie, Querleu, Denis, Dagonnet, Francoise, Fournié, Jean-Jacques, Marie, Jean-Pierre, Pujade-Lauraine, Eric, Favre, Gilles, Soria, Jeanine, Mirshahi, Massoud
Format:	Artikel
Sprache:	eng
Schlagworte:	Actors Aged B cells Biological Assay Cancer Cancer metastasis CD29 antigen CD9 antigen Cell Adhesion Cell adhesion & migration Cell Biology Cell Biology/Cell Adhesion Cell Biology/Cellular Death and Stress Responses Cell Communication Cell Line, Tumor Cell Separation Chemoresistance Chemotherapy Claudius Colorectal cancer Cytotoxicity Development and progression Dilution Drug resistance Drug Resistance, Neoplasm Endothelium Epithelium - pathology Epithelium - ultrastructure Female Genotype & phenotype Growth factors Hematology Homeostasis Human health and pathology Humans Intracellular Membranes - metabolism Life Sciences Lymphocytes Lymphoma Medical research Melanoma Metastases Metastasis Middle Aged Multidrug resistance Multidrug Resistance-Associated Proteins - metabolism Oncology/Gynecological Cancers Ovarian cancer Ovarian carcinoma Ovarian Neoplasms - drug therapy Ovarian Neoplasms - pathology Ovarian Neoplasms - ultrastructure Patients Peritoneum Pharmacology/Drug Resistance Phenotype Phenotypes Plasma membranes Proteins Stem cells Stromal cells Stromal Cells - pathology Stromal Cells - ultrastructure Tumors Women's Health/Gynecological Cancers
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