Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes

Human embryonic stem cells (hESCs) can serve as a potentially limitless source of cells that may enable regeneration of diseased tissue and organs. Here we investigate the use of human embryonic stem cell-derived cardiomyocytes (hESC-CMs) in promoting recovery from cardiac ischemia reperfusion injur...

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Veröffentlicht in:	PloS one 2008-10, Vol.3 (10), p.e3474
Hauptverfasser:	Cao, Feng, Wagner, Roger A, Wilson, Kitchener D, Xie, Xiaoyan, Fu, Ji-Dong, Drukker, Micha, Lee, Andrew, Li, Ronald A, Gambhir, Sanjiv S, Weissman, Irving L, Robbins, Robert C, Wu, Joseph C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioengineering Biological activity Cardiology Cardiomyocytes Cardiovascular Disorders/Cardiovascular Imaging Cardiovascular Disorders/Coronary Artery Disease Cardiovascular Disorders/Heart Failure Cell Biology/Gene Expression Cell Differentiation Cell survival Clinical trials Developmental biology Developmental Biology/Cell Differentiation Developmental Biology/Stem Cells DNA microarrays Drosophila Electrocardiography Embryo cells Embryonic stem cells Embryonic Stem Cells - cytology Embryonic Stem Cells - transplantation Engraftment Fetuses Gene expression Gene Expression Profiling Genes Genetic aspects Genetic research Genetics and Genomics/Bioinformatics Genetics and Genomics/Gene Expression Genomics Graft Survival Heart Heart cells Heart diseases Heart failure Heart function Humans In vivo methods and tests Insects Ischemia Localization Mice MicroRNAs Models, Animal Myocardial Reperfusion Injury - therapy Myocytes, Cardiac - cytology Myocytes, Cardiac - transplantation Nuclear medicine Oligonucleotide Array Sequence Analysis Organs Regeneration Reperfusion Stem cell transplantation Stem Cell Transplantation - methods Stem cells Therapeutic applications Transcription Transcription (Genetics) Transcription, Genetic Transplantation Transplantation, Heterologous Treatment Outcome
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