Effectiveness of cellulose sulfate vaginal gel for the prevention of HIV infection: results of a Phase III trial in Nigeria

This trial evaluated the safety and effectiveness of 6% cellulose sulfate vaginal gel in preventing male-to-female vaginal transmission of HIV, gonorrhea and chlamydial infection. This Phase III, double-blind, randomized, placebo-controlled trial was conducted between November 2004 and March 2007 in...

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Veröffentlicht in:	PloS one 2008-11, Vol.3 (11), p.e3784
Hauptverfasser:	Halpern, Vera, Ogunsola, Folasade, Obunge, Orikomaba, Wang, Chin-Hua, Onyejepu, Nneka, Oduyebo, Oyinola, Taylor, Doug, McNeil, Linda, Mehta, Neha, Umo-Otong, John, Otusanya, Sakiru, Crucitti, Tania, Abdellati, Said
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Cellulose Cellulose - administration & dosage Cellulose - adverse effects Cellulose - analogs & derivatives Chlamydia Chlamydia infections Chlamydia Infections - prevention & control Chlamydia Infections - transmission Clinical trials Coitus Condoms Disease prevention Disease transmission Double-Blind Method Female Gonorrhea Gonorrhea - prevention & control Gonorrhea - transmission Health aspects Health risk assessment Health risks HIV HIV antibodies HIV Infections - prevention & control HIV Infections - transmission Human immunodeficiency virus Humans Infections Infectious Diseases/HIV Infection and AIDS Infectious Diseases/Sexually Transmitted Diseases Informed consent Male Nigeria Population studies Pregnancy Product development Randomization Safety Sexually transmitted diseases Statistical analysis Statistical significance STD Sulfates Treatment Outcome Vagina Vaginal Creams, Foams, and Jellies Women's Health/Sexually Transmitted Diseases Young Adult
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