Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth

MicroRNAs (miRNAs) play important roles in cancer development. By cloning and sequencing of a HPV16(+) CaSki cell small RNA library, we isolated 174 miRNAs (including the novel miR-193c) which could be grouped into 46 different miRNA species, with miR-21, miR-24, miR-27a, and miR-205 being most abun...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2008-07, Vol.3 (7), p.e2557-e2557
Hauptverfasser:	Wang, Xiaohong, Tang, Shuang, Le, Shu-Yun, Lu, Robert, Rader, Janet S, Meyers, Craig, Zheng, Zhi-Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Acquired immune deficiency syndrome AIDS Analysis Base Sequence Biotechnology Cancer Carcinogenesis Carcinogens Cell culture Cell Line, Tumor Cell proliferation Cervical cancer Cloning Correlation Deoxyribonucleic acid Deregulation Development and progression DNA Down-Regulation Female Gene Expression Gene Expression Profiling Gene sequencing Genomes Genomics Growth HIV Human immunodeficiency virus Human papillomavirus Humans Libraries Medical research Medical screening MicroRNA MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA Molecular Sequence Data Papillomavirus infections Ribonucleic acid RNA RNA polymerase Rodents Tissues Transcription factors Tumors Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - metabolism Viral infections Virology/Viruses and Cancer
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!