Clathrin- and caveolin-independent entry of human papillomavirus type 16--involvement of tetraspanin-enriched microdomains (TEMs)

Infectious entry of human papillomaviruses into their host cells is an important step in the viral life cycle. For cell binding these viruses use proteoglycans as initial attachment sites. Subsequent transfer to a secondary receptor molecule seems to be involved in virus uptake. Depending on the pap...

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Veröffentlicht in:	PloS one 2008-10, Vol.3 (10), p.e3313-e3313
Hauptverfasser:	Spoden, Gilles, Freitag, Kirsten, Husmann, Matthias, Boller, Klaus, Sapp, Martin, Lambert, Carsten, Florin, Luise
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens, CD - metabolism Antigens, CD - ultrastructure Breast cancer Caveolae - metabolism Caveolae - virology Caveolin CD63 antigen Cell adhesion Cell adhesion & migration Cell Biology Cell Line Cell surface Cervical cancer Cervix Clathrin Clathrin - genetics Clathrin - metabolism Deoxyribonucleic acid Development and progression DNA Dynamin Endocytosis Etiology Female Gene expression Health aspects HeLa Cells Heparan sulfate Hepatitis Hepatitis C Hepatitis C virus HIV Human immunodeficiency virus Human papillomavirus Human papillomavirus 16 Human papillomavirus 16 - genetics Human papillomavirus 16 - metabolism Human papillomavirus 16 - pathogenicity Human papillomavirus 16 - ultrastructure Humans Hygiene Immunization Immunofluorescence Immunoglobulins Infection Infections Infectious diseases Infectious Diseases/Sexually Transmitted Diseases Infectious Diseases/Viral Infections Inhibition Kidney - cytology Leukemia Life cycle engineering Life cycles Lipids Membrane Microdomains - metabolism Membrane Microdomains - ultrastructure Membrane Proteins - metabolism Membrane Proteins - ultrastructure Microbiology/Cellular Microbiology and Pathogenesis Mutants Papillomaviridae Papillomavirus Papillomavirus infections Pathogens Platelet Membrane Glycoproteins - metabolism Platelet Membrane Glycoproteins - ultrastructure Proteins Proteoglycans siRNA Tetraspanin 24 Tetraspanin 30 Virion - genetics Virion - metabolism Virion - ultrastructure Virology/Host Invasion and Cell Entry Virus Internalization Viruses
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