Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells

Pluripotent embryonic stem (ES) cells, which have the capacity to give rise to all tissue types in the body, show great promise as a versatile source of cells for regenerative therapy. However, the basic mechanisms of lineage specification of pluripotent stem cells are largely unknown, and generatin...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2008-08, Vol.3 (8), p.e2904-e2904
Hauptverfasser:	Hao, Jijun, Daleo, Marie A, Murphy, Clare K, Yu, Paul B, Ho, Joshua N, Hu, Jianyong, Peterson, Randall T, Hatzopoulos, Antonis K, Hong, Charles C
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anemia, Iron-Deficiency - blood Anemia, Iron-Deficiency - epidemiology Blood Transfusion Bone morphogenetic proteins Bone Morphogenetic Proteins - antagonists & inhibitors Cardiology Cardiomyocytes Cell Biology/Cell Signaling Cell Biology/Developmental Molecular Mechanisms Cell differentiation Cell Differentiation - drug effects Cell signaling Chemical Biology Child, Hospitalized Child, Preschool Collaboration Developmental biology Developmental Biology/Cell Differentiation Developmental Biology/Stem Cells Developmental stages Differentiation (biology) Embryo cells Embryonic stem cells Embryonic Stem Cells - cytology Embryonic Stem Cells - drug effects Embryos Female Heart Heart diseases Hemoglobins - metabolism Humans Infant Inhibitors Kinases Male Medicine Metabolism Modulators Myocytes, Cardiac - cytology Myocytes, Cardiac - drug effects Myogenesis Noggin protein Pharmacology Physicians Pluripotency Proteins Pyrazoles - pharmacology Pyrimidines - pharmacology Regenerative medicine Signal transduction Signal Transduction - drug effects Smooth muscle Specifications Stem cell research Stem cell transplantation Stem cells Tissue engineering Urban Population
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!