The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase

The target of rapamycin (Tor) protein plays central roles in cell growth. Rapamycin inhibits cell growth and promotes cell cycle arrest at G1 (G0). However, little is known about whether Tor is involved in other stages of the cell division cycle. Here we report that the rapamycin-sensitive Tor compl...

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Veröffentlicht in:	PloS one 2008-05, Vol.3 (5), p.e2223-e2223
Hauptverfasser:	Nakashima, Akio, Maruki, Yoshiko, Imamura, Yuko, Kondo, Chika, Kawamata, Tomoko, Kawanishi, Ippei, Takata, Hideki, Matsuura, Akira, Lee, Kyung S, Kikkawa, Ushio, Ohsumi, Yoshinori, Yonezawa, Kazuyoshi, Kamada, Yoshiaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Baking yeast Biochemistry/Cell Signaling and Trafficking Structures Cancer Cell Biology/Cell Signaling Cell Biology/Microbial Growth and Development Cell cycle Cell Cycle Proteins - metabolism Cell Division Cell growth G2 Phase Genetics and Genomics Kinases Localization Membrane Proteins - genetics Molecular Biology Nuclear transport Phosphatases Polo Polo-like kinase Protein Kinases - metabolism Protein-Serine-Threonine Kinases - metabolism Rapamycin Saccharomyces cerevisiae Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Signal Transduction TOR protein Translocation Yeast
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