Ca2+/calmodulin-dependent kinase kinase alpha is expressed by monocytic cells and regulates the activation profile

Macrophages are capable of assuming numerous phenotypes in order to adapt to endogenous and exogenous challenges but many of the factors that regulate this process are still unknown. We report that Ca(2+)/calmodulin-dependent kinase kinase alpha (CaMKKalpha) is expressed in human monocytic cells and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2008-02, Vol.3 (2), p.e1606
Hauptverfasser:	Guest, Christopher B, Deszo, Eric L, Hartman, Matthew E, York, Jason M, Kelley, Keith W, Freund, Gregory G
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Active Transport, Cell Nucleus Affinity chromatography Animal sciences Antigens, CD - analysis Beads Calcium Calcium-binding protein Calcium-Calmodulin-Dependent Protein Kinase Kinase - analysis Calcium-Calmodulin-Dependent Protein Kinase Kinase - antagonists & inhibitors Calcium-Calmodulin-Dependent Protein Kinase Kinase - physiology Calmodulin CD11b antigen CD86 antigen Cell activation Cell Biology/Cell Signaling Cell Biology/Leukocyte Signaling and Gene Expression Cell Differentiation Cells, Cultured Chromatography Cytokines Dendritic cells Enzyme Inhibitors - pharmacology Epidermal growth factor Forskolin Humans Immunology Immunology/Leukocyte Activation Immunology/Leukocyte Signaling and Gene Expression Inhibition Interleukin 10 Interleukin-10 - biosynthesis Kinases Leukemia Lysates Macrophages Mass spectrometry Mass spectroscopy Monocytes Monocytes - chemistry Monocytes, Activated Killer Phosphorylation Proteins siRNA Studies Tetradecanoylphorbol Acetate - pharmacology Translocation Tumor Necrosis Factor-alpha - biosynthesis Tumor necrosis factor-α
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!