Oxidative stress accumulates in adipose tissue during aging and inhibits adipogenesis

Aging constitutes a major independent risk factor for the development of type 2 diabetes and is accompanied by insulin resistance and adipose tissue dysfunction. One of the most important factors implicitly linked to aging and age-related chronic diseases is the accumulation of oxidative stress. How...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2011-04, Vol.6 (4), p.e18532-e18532
Hauptverfasser:	Findeisen, Hannes M, Pearson, Kevin J, Gizard, Florence, Zhao, Yue, Qing, Hua, Jones, Karrie L, Cohn, Dianne, Heywood, Elizabeth B, de Cabo, Rafael, Bruemmer, Dennis
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Accumulation Adipocytes Adipogenesis Adipose tissue Adipose Tissue - growth & development Adipose Tissue - metabolism Age Aging Aging - metabolism Animals Apoptosis Base Sequence Bioaccumulation Biological effects Biology Body Composition Body fat Cancer Cell culture Cell cycle Cell proliferation Chromatin Immunoprecipitation Chronic diseases Chronic illnesses Development and progression Diabetes Diabetes mellitus Differentiation DNA Primers E2F protein Gene expression Genes Glucose Glutathione Glutathione - metabolism Homeostasis Inhibition Insulin Insulin resistance Kinases Male Medicine Metabolism Mice Mice, Inbred C57BL Obesity Oxidative Stress Phase transitions Phosphorylation Promoter Regions, Genetic Retina Retinoblastoma Retinoblastoma protein Reverse Transcriptase Polymerase Chain Reaction Risk factors Rodents S phase Transcription Transcription (Genetics) Transcription factors Type 2 diabetes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!