Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish

A major obstacle in treating drug addiction is the severity of opiate withdrawal syndrome, which can lead to unwanted relapse. Mitragynine is the major alkaloid compound found in leaves of Mitragyna speciosa, a plant widely used by opiate addicts to mitigate the harshness of drug withdrawal. A serie...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2011-12, Vol.6 (12), p.e28340
Hauptverfasser:	Khor, Beng-Siang, Jamil, Mohd Fadzly Amar, Adenan, Mohamad Ilham, Shu-Chien, Alexander Chong
Format:	Artikel
Sprache:	eng
Schlagworte:	Addicts Analysis Animal behavior Animals Anxiety Anxiety - drug therapy Attenuation Behavior, Animal - drug effects Biology Brain Conditioning (Psychology) - drug effects Corticotropin-releasing hormone Cortisol Danio rerio Diving Drug abuse Drug addiction Enkephalins - genetics Exploratory behavior Female Gene expression Gene Expression Regulation - drug effects Genetic aspects Glucocorticoids Hydrocortisone - biosynthesis Hydrocortisone - metabolism Leaves Male Medicine Mitragyna speciosa Morphine Morphine - pharmacology Neurophysiology Neurosciences Pharmaceuticals Prodynorphin Protein Precursors - genetics Receptors Receptors, Corticotropin-Releasing Hormone - genetics RNA RNA, Messenger - genetics RNA, Messenger - metabolism Rodents Science Secologanin Tryptamine Alkaloids - pharmacology Secologanin Tryptamine Alkaloids - therapeutic use Spatial Behavior - drug effects Stress Stresses Substance Withdrawal Syndrome - drug therapy Substance Withdrawal Syndrome - genetics Substance Withdrawal Syndrome - metabolism Substance Withdrawal Syndrome - psychology Swimming Swimming behavior Withdrawal Zebrafish
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!