Autophagy in human embryonic stem cells

Autophagy (macroautophagy) is a degradative process that involves the sequestration of cytosolic material including organelles into double membrane vesicles termed autophagosomes for delivery to the lysosome. Autophagy is essential for preimplantation development of mouse embryos and cavitation of e...

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Veröffentlicht in:	PloS one 2011-11, Vol.6 (11), p.e27485
Hauptverfasser:	Tra, Thien, Gong, Lan, Kao, Lin-Pin, Li, Xue-Lei, Grandela, Catarina, Devenish, Rodney J, Wolvetang, Ernst, Prescott, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy Biochemistry Bioengineering Biology Biomarkers - metabolism Bone morphogenetic proteins Cavitation Cell death Cell Differentiation Cell Line Cell lines Cloning Differentiation Embryo cells Embryogenesis Embryonic growth stage Embryonic stem cells Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Embryos Fluorescence Fluorescent indicators Genes, Reporter - genetics Genomics Homeostasis Humans Labeling Labelling Liver cancer Membrane vesicles Mice Microtubule-Associated Proteins - genetics Molecular biology Nanotechnology Organelles Phagocytosis Phagosomes Pluripotency Rapamycin Recombinant Fusion Proteins - genetics Reproducibility of Results Stem cell transplantation Stem cells Transforming growth factor-b Transforming growth factors Wortmannin
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