Honey bee dopamine and octopamine receptors linked to intracellular calcium signaling have a close phylogenetic and pharmacological relationship

Three dopamine receptor genes have been identified that are highly conserved among arthropod species. One of these genes, referred to in honey bees as Amdop2, shows a close phylogenetic relationship to the a-adrenergic-like octopamine receptor family. In this study we examined in parallel the functi...

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Veröffentlicht in:	PloS one 2011-11, Vol.6 (11), p.e26809-e26809
Hauptverfasser:	Beggs, Kyle T, Tyndall, Joel D A, Mercer, Alison R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analysis Animals Apis mellifera Aplysia Arthropoda Arthropods Bees Binding Sites Biology Caenorhabditis elegans Calcium Calcium (intracellular) Calcium - metabolism Calcium Signaling - genetics Calcium Signaling - physiology Calcium signalling Cell Line Conservation Cyclic adenosine monophosphate Cyclic AMP Cyclic AMP - metabolism Dibenzazepines - metabolism Dopamine Dopamine receptors Drosophila Drosophila melanogaster European honeybee Family relations Flupenthixol Flupenthixol - pharmacology Genes Genetic algorithms Honey Humans Imidazoles - metabolism Insects Intracellular Intracellular signalling Mianserin Molecular Sequence Data Nervous system Octopamine Octopamine receptors Oils & fats Pharmacology Phenols (Class of compounds) Phospholipase Phospholipase C Phylogenetics Phylogeny Properties (attributes) Proteins Receptor mechanisms Receptors Receptors, Biogenic Amine - chemistry Receptors, Biogenic Amine - classification Receptors, Biogenic Amine - genetics Receptors, Biogenic Amine - metabolism Receptors, Dopamine - chemistry Receptors, Dopamine - classification Receptors, Dopamine - genetics Receptors, Dopamine - metabolism Sequence Homology, Amino Acid Signal transduction Signal Transduction - drug effects Spiperone Spiperone - pharmacology Tyramine Wildlife conservation Zoology
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