Gene decay in Shigella as an incipient stage of host-adaptation

Many facultative bacterial pathogens have undergone extensive gene decay processes, possibly due to lack of selection pressure during evolutionary conversion from free-living to intracellular lifestyle. Shigella, the causative agents of human shigellosis, have arisen from different E. coli-like ance...

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Veröffentlicht in:	PloS one 2011-11, Vol.6 (11), p.e27754-e27754
Hauptverfasser:	Feng, Ye, Chen, Zhe, Liu, Shu-Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation Adaptation, Physiological - genetics Analysis Bacteria Bacterial Proteins - genetics Biology Chinese medicine Clonal deletion Convergence Deactivation Decay Deoxyribonucleic acid DNA E coli Escherichia coli Gene deletion Gene expression Gene Expression Regulation, Bacterial - genetics Genes Genes, Bacterial - genetics Genetic aspects Genetic engineering Genomes Genomics Host-Pathogen Interactions - genetics Humans Inactivation Leprosy Medical research Membrane proteins Mutation Operon - genetics Operons Pathogens Phylogenetics Prokaryotes Proteins Pseudogenes Pseudogenes - genetics Salmonella Shigella Shigella - genetics Shigella - physiology Shigellosis
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