NASA-approved rotary bioreactor enhances proliferation of human epidermal stem cells and supports formation of 3D epidermis-like structure

The skin is susceptible to different injuries and diseases. One major obstacle in skin tissue engineering is how to develop functional three-dimensional (3D) substitute for damaged skin. Previous studies have proved a 3D dynamic simulated microgravity (SMG) culture system as a "stimulatory"...

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Veröffentlicht in:	PloS one 2011-11, Vol.6 (11), p.e26603-e26603
Hauptverfasser:	Lei, Xiao-hua, Ning, Li-na, Cao, Yu-jing, Liu, Shuang, Zhang, Shou-bing, Qiu, Zhi-fang, Hu, Hui-min, Zhang, Hui-shan, Liu, Shu, Duan, En-kui
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biology Biomedical materials Bioreactors Bones Carriers Cell culture Cell Culture Techniques Cell cycle Cell Differentiation - physiology Cell growth Cell Proliferation Children Colonies Differentiation Disease susceptibility Efficiency Epidermis Epidermis - cytology Epidermis - metabolism FDA approval Fluorescent Antibody Technique Humans Integrin beta1 - metabolism Laboratories Lei, Li Medicine Microgravity R&D Research & development Skin Stem cells Stem Cells - cytology Stem Cells - metabolism Studies Tissue engineering Viability Wound healing Zoology
Online-Zugang:	Volltext
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