A blood-based screening tool for Alzheimer's disease that spans serum and plasma: findings from TARC and ADNI

There is no rapid and cost effective tool that can be implemented as a front-line screening tool for Alzheimer's disease (AD) at the population level. To generate and cross-validate a blood-based screener for AD that yields acceptable accuracy across both serum and plasma. Analysis of serum bio...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2011-12, Vol.6 (12), p.e28092
Hauptverfasser:	O'Bryant, Sid E, Xiao, Guanghua, Barber, Robert, Huebinger, Ryan, Wilhelmsen, Kirk, Edwards, Melissa, Graff-Radford, Neill, Doody, Rachelle, Diaz-Arrastia, Ramon
Format:	Artikel
Sprache:	eng
Schlagworte:	Advertising executives Aged Aged, 80 and over Aging Algorithms Alzheimer Disease - blood Alzheimer Disease - diagnosis Alzheimer's disease Apolipoprotein E Apolipoprotein E4 Apolipoprotein E4 - genetics Apolipoproteins Archives & records Area Under Curve Biology Biomarkers Biomarkers - blood Biomedical laboratories Blood Blood proteins Brain research Cerebrospinal fluid Cerebrospinal Fluid - metabolism Cholesterol Cognitive ability Cohort Studies Computational Biology - methods Consortia Dementia Demographics Disease control FDA approval Female Health sciences Health screening Homocysteine Humans Likelihood Functions Likelihood ratio Male Mass Screening - methods Medical imaging Medical research Medical tests Medicine Middle Aged Neurobiology Neurodegenerative diseases Neuroimaging Neurology Neurosciences Pathology Plasma Plasma - metabolism Plasma proteins Predictive Value of Tests Primary care Proteins Proteomics Risk Screening Sensitivity and Specificity Serum - metabolism Tau protein Texas Training Triglycerides
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!