Beta-catenin accelerates human papilloma virus type-16 mediated cervical carcinogenesis in transgenic mice

Human papilloma virus (HPV) is the principal etiological agent of cervical cancer in women, and its DNA is present in virtually all of these tumors. However, exposure to the high-risk HPV types alone is insufficient for tumor development. Identifying specific collaborating factors that will lead to...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2011-11, Vol.6 (11), p.e27243
Hauptverfasser:	Bulut, Gülay, Fallen, Shannon, Beauchamp, Elspeth M, Drebing, Lauren E, Sun, Junfeng, Berry, Deborah L, Kallakury, Bhaskar, Crum, Christopher P, Toretsky, Jeffrey A, Schlegel, Richard, Üren, Aykut
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Animal models Animals beta Catenin - physiology Biology Bladder cancer Cancer Carcinogenesis Carcinogens Cell Transformation, Neoplastic Cervical cancer Cervix Coding Deoxyribonucleic acid Disease Models, Animal Disease Progression DNA Dysplasia Early region Epigenetics Epithelial cells Estrogens Estrogens - pharmacology Etiology Female Genes Genetic engineering Human papillomavirus Human papillomavirus 16 Humans Invasiveness Keratin Lesions Medicine Mice Mice, Transgenic Oral cancer Papillomavirus E7 Proteins Papillomavirus infections Pathology Phenotype Proteins Rodents Studies Transgenic animals Transgenic mice Tumors Uterine Cervical Neoplasms - etiology Uterine Cervical Neoplasms - virology Viruses Wnt protein Wnt Signaling Pathway β-Catenin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!