A two-compartment model of VEGF distribution in the mouse

Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis--the growth of new microvessels from existing microvasculature. Angiogenesis is a complex process involving numerous molecular species, and to better understand it, a systems biology approach is necessary. In vivo preclinic...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2011-11, Vol.6 (11), p.e27514
Hauptverfasser:	Yen, Phillip, Finley, Stacey D, Engel-Stefanini, Marianne O, Popel, Aleksander S
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Angiogenesis Angiogenesis Inhibitors Angiogenic Proteins Animal models Animal tissues Animals Biology Biomedical engineering Blood Cardiovascular disease Cell adhesion & migration Compartments Computational neuroscience Computer simulation Data processing Drug development Endothelial cells Endothelium Engineering Esophageal cancer Experimental data Extracellular matrix Hypertension In vivo methods and tests Isoforms Kinases Macromolecules Medicine Mice Microvasculature Models, Biological Mouse devices Musculoskeletal system Neuropilin Neuropilin-1 - metabolism Parameter estimation Parameter sensitivity Peptide Fragments - metabolism Permeability Protein Binding Receptors Rodents Secretion Sensitivity analysis Simulation Skeletal muscle Studies Tissue Distribution Tissues Tumors Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism Vascular Endothelial Growth Factor Receptor-1 - metabolism Vascular Endothelial Growth Factor Receptor-2 - metabolism Vascular endothelial growth factor receptors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!