From SOMAmer-based biomarker discovery to diagnostic and clinical applications: a SOMAmer-based, streamlined multiplex proteomic assay

Recently, we reported a SOMAmer-based, highly multiplexed assay for the purpose of biomarker identification. To enable seamless transition from highly multiplexed biomarker discovery assays to a format suitable and convenient for diagnostic and life-science applications, we developed a streamlined,...

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Veröffentlicht in:	PloS one 2011-10, Vol.6 (10), p.e26332-e26332
Hauptverfasser:	Kraemer, Stephan, Vaught, Jonathan D, Bock, Christopher, Gold, Larry, Katilius, Evaldas, Keeney, Tracy R, Kim, Nancy, Saccomano, Nicholas A, Wilcox, Sheri K, Zichi, Dom, Sanders, Glenn M
Format:	Artikel
Sprache:	eng
Schlagworte:	Assaying Automation Biological Assay - methods Biology Biomarkers Biomarkers - analysis Case-Control Studies Deoxyribonucleic acid Diagnostic software Diagnostic systems Diagnostic Techniques and Procedures DNA DNA polymerase Humans Hybridization Laboratories Ligands Limit of Detection Lung cancer Medical diagnosis Medicine Multiplexing Nucleic Acids - metabolism Oligonucleotides - chemistry Oligonucleotides - metabolism Population Proteins Proteomics Proteomics - methods Reproducibility of Results Therapeutic applications Titrimetry
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