Characteristics of stem cells derived from the degenerated human intervertebral disc cartilage endplate

Mesenchymal stem cells (MSCs) derived from adult tissues are an important candidate for cell-based therapies and regenerative medicine due to their multipotential differentiation capability. MSCs have been identified in many adult tissues but have not reported in the human intervertebral disc cartil...

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Veröffentlicht in:	PloS one 2011-10, Vol.6 (10), p.e26285-e26285
Hauptverfasser:	Liu, Lan-Tao, Huang, Bo, Li, Chang-Qing, Zhuang, Ying, Wang, Jian, Zhou, Yue
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipogenesis Adult Back pain Biocompatibility Biology Biomedical materials Bone marrow Bone Marrow Cells - cytology Calcification Cartilage Cartilage - pathology Cell culture Cell Cycle Cell Proliferation Cell surface Chondrocytes Chondrogenesis Clusters Comparative analysis Cytology Degeneration Differentiation Epitopes Extracellular matrix Female Gene expression Gene Expression Regulation Gene therapy Hospitals Humans Intervertebral Disc - pathology Intervertebral Disc - surgery Intervertebral Disc Degeneration - pathology Intervertebral Disc Degeneration - surgery Intervertebral discs Lumbar Vertebrae - pathology Lumbar Vertebrae - surgery Male Medicine Mesenchymal stem cells Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - metabolism Mesenchyme Middle Aged Mineralization Orthopedics Osteoblasts Osteogenesis Regenerative medicine Stem cells Suspension culture Tissue engineering Transcription factors
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