Intracellular ROS protection efficiency and free radical-scavenging activity of curcumin

Curcumin has many pharmaceutical applications, many of which arise from its potent antioxidant properties. The present research examined the antioxidant activities of curcumin in polar solvents by a comparative study using ESR, reduction of ferric iron in aqueous medium and intracellular ROS/toxicit...

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Veröffentlicht in:	PloS one 2011-10, Vol.6 (10), p.e26012
Hauptverfasser:	Barzegar, Abolfazl, Moosavi-Movahedi, Ali A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Alzheimers disease Animals Antioxidants Antioxidants (Nutrients) Benzhydryl Compounds - metabolism Biology Cell Line Chemistry Comparative studies Cumene Cumene hydroperoxide Curcumin Curcumin - metabolism Curcumin - pharmacology Cytoplasm Cytoprotection - drug effects Diabetes Electron Spin Resonance Spectroscopy Electron transfer Electrons Extracellular Space - drug effects Extracellular Space - metabolism Free Radical Scavengers - metabolism Free Radical Scavengers - pharmacology Free radicals Functional groups Hydrogen peroxide Insulin Intracellular Intracellular Space - drug effects Intracellular Space - metabolism Iron Iron compounds Lethal effects Lipid peroxidation Lipids Lipophilic Metabolism Methods Myoblasts - cytology Myoblasts - drug effects Myoblasts - metabolism Phenolic compounds Phenols Rats Reactive Oxygen Species - metabolism Rodents Scavenging Steric hindrance Studies Toxicity Vitamin E
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