Implementing prenatal diagnosis based on cell-free fetal DNA: accurate identification of factors affecting fetal DNA yield

Cell-free fetal DNA is a source of fetal genetic material that can be used for non-invasive prenatal diagnosis. Usually constituting less than 10% of the total cell free DNA in maternal plasma, the majority is maternal in origin. Optimizing conditions for maximizing yield of cell-free fetal DNA will...

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Veröffentlicht in:PloS one 2011-10, Vol.6 (10), p.e25202-e25202
Hauptverfasser: Barrett, Angela N, Zimmermann, Bernhard G, Wang, Darrell, Holloway, Andrew, Chitty, Lyn S
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Sprache:eng
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