When and where of auditory spatial processing in cortex: a novel approach using electrotomography
The modulation of brain activity as a function of auditory location was investigated using electro-encephalography in combination with standardized low-resolution brain electromagnetic tomography. Auditory stimuli were presented at various positions under anechoic conditions in free-field space, thu...
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| description | The modulation of brain activity as a function of auditory location was investigated using electro-encephalography in combination with standardized low-resolution brain electromagnetic tomography. Auditory stimuli were presented at various positions under anechoic conditions in free-field space, thus providing the complete set of natural spatial cues. Variation of electrical activity in cortical areas depending on sound location was analyzed by contrasts between sound locations at the time of the N1 and P2 responses of the auditory evoked potential. A clear-cut double dissociation with respect to the cortical locations and the points in time was found, indicating spatial processing (1) in the primary auditory cortex and posterodorsal auditory cortical pathway at the time of the N1, and (2) in the anteroventral pathway regions about 100 ms later at the time of the P2. Thus, it seems as if both auditory pathways are involved in spatial analysis but at different points in time. It is possible that the late processing in the anteroventral auditory network reflected the sharing of this region by analysis of object-feature information and spectral localization cues or even the integration of spatial and non-spatial sound features. |
| doi_str_mv | 10.1371/journal.pone.0025146 |
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Auditory stimuli were presented at various positions under anechoic conditions in free-field space, thus providing the complete set of natural spatial cues. Variation of electrical activity in cortical areas depending on sound location was analyzed by contrasts between sound locations at the time of the N1 and P2 responses of the auditory evoked potential. A clear-cut double dissociation with respect to the cortical locations and the points in time was found, indicating spatial processing (1) in the primary auditory cortex and posterodorsal auditory cortical pathway at the time of the N1, and (2) in the anteroventral pathway regions about 100 ms later at the time of the P2. Thus, it seems as if both auditory pathways are involved in spatial analysis but at different points in time. 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| subjects | Acoustic Stimulation Adult Auditory Cortex - physiology Auditory evoked potentials Auditory pathways Auditory Pathways - physiology Auditory stimuli Auditory system Biology Brain Brain Mapping Brain research Cortex (auditory) Cues Dissociation EEG Electromagnetism Evoked Potentials, Auditory - physiology Female Functional Laterality Humans Hypotheses Information processing Localization Male Medical imaging NMR Nuclear magnetic resonance Reaction Time Social and Behavioral Sciences Sound Sound Localization - physiology Spatial analysis Studies Topography Young Adult |
| title | When and where of auditory spatial processing in cortex: a novel approach using electrotomography |
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