A test of the coordinated expression hypothesis for the origin and maintenance of the GAL cluster in yeast

Metabolic gene clusters--functionally related and physically clustered genes--are a common feature of some eukaryotic genomes. Two hypotheses have been advanced to explain the origin and maintenance of metabolic gene clusters: coordinated gene expression and genetic linkage. Here we test the hypothe...

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Veröffentlicht in:	PloS one 2011-09, Vol.6 (9), p.e25290-e25290
Hauptverfasser:	Lang, Gregory I, Botstein, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Ascomycota Aspergillus Baking yeast Biology Cellular biology Clustering Clusters Enzymes Fitness Fungi Galactokinase - genetics Galactose Gene clusters Gene expression Genes Genomes Genomics Glucose Hypotheses Maintenance Metabolism Metabolites Multigene Family - genetics Population genetics Reproductive fitness Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins - genetics Saccharomyces paradoxus Standard deviation Trans-Activators - genetics Yeast Yeasts
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