Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates

Genome-wide association (GWA) studies have identified a number of loci underlying variation in human serum uric acid (SUA) levels with the SLC2A9 gene having the largest effect identified so far. Gene-gene interactions (epistasis) are largely unexplored in these GWA studies. We performed a full pair...

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Veröffentlicht in:PloS one 2011-08, Vol.6 (8), p.e23836
Hauptverfasser: Wei, Wenhua, Hemani, Gibran, Hicks, Andrew A, Vitart, Veronique, Cabrera-Cardenas, Claudia, Navarro, Pau, Huffman, Jennifer, Hayward, Caroline, Knott, Sara A, Rudan, Igor, Pramstaller, Peter P, Wild, Sarah H, Wilson, James F, Campbell, Harry, Dunlop, Malcolm G, Hastie, Nicholas, Wright, Alan F, Haley, Chris S
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Sprache:eng
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