A novel multiplex real-time PCR for the identification of mycobacteria associated with zoonotic tuberculosis

Tuberculosis (TB) is the leading cause of death worldwide from a single infectious agent. An ability to detect the Mycobacterium tuberculosis complex (MTC) in clinical material while simultaneously differentiating its members is considered important. This allows for the gathering of epidemiological...

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Veröffentlicht in:	PloS one 2011-08, Vol.6 (8), p.e23481-e23481
Hauptverfasser:	Reddington, Kate, O'Grady, Justin, Dorai-Raj, Siobhan, Niemann, Stefan, van Soolingen, Dick, Barry, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Assaying Bacillus Calmette-Guerin vaccine BCG Biology Biomedical engineering Cattle Chemotherapy Developing countries Differentiation Disease transmission DNA Primers DNA, Bacterial - chemistry DNA, Bacterial - genetics Engineering Epidemiology Genomics Geographical distribution Health aspects Humans Identification Industrialized nations Infections LDCs Medicine Multiplexing Mycobacterium Mycobacterium - classification Mycobacterium - genetics Mycobacterium bovis Mycobacterium bovis - genetics Mycobacterium tuberculosis Mycobacterium tuberculosis - genetics Phylogeny Real time Real-Time Polymerase Chain Reaction - methods Reproducibility of Results Science Sensitivity and Specificity Sequence Analysis, DNA Species Specificity Target recognition Tuberculosis Tuberculosis - diagnosis Tuberculosis - microbiology Tuberculosis, Bovine - microbiology Veterinary Science Zoonoses Zoonoses - microbiology
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