Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns

The blind subterranean mole rat (Spalax ehrenbergi superspecies) is a model animal for survival under extreme environments due to its ability to live in underground habitats under severe hypoxic stress and darkness. Here we report the transcriptome sequencing of Spalax galili, a chromosomal type of...

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Veröffentlicht in:	PloS one 2011-08, Vol.6 (8), p.e21227
Hauptverfasser:	Malik, Assaf, Korol, Abraham, Hübner, Sariel, Hernandez, Alvaro G, Thimmapuram, Jyothi, Ali, Shahjahan, Glaser, Fabian, Paz, Arnon, Avivi, Aaron, Band, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive radiation Alternative splicing Animals Bands Base Sequence Biological evolution Biology Brain Brain - metabolism Brain research Cell cycle Darkness DNA, Complementary - chemistry DNA, Complementary - genetics Evolution Evolution, Molecular Extreme environments Gene expression Gene Expression Profiling - methods Gene Library Genes Genomes Genomics Homology Humans Hypoxia Medical research Mice Molecular Sequence Data Morphology Muscles Muscles - metabolism Musculoskeletal system Mutation Open Reading Frames - genetics Pan troglodytes Polymorphism, Single Nucleotide Proteins Radiation Rats Rattus Rodents Sensors Sequence Analysis, DNA - methods Single-nucleotide polymorphism Spalax Spalax - genetics Tissues Transcriptome Trends Underground utilities
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