Serum cholesterol and the progression of Parkinson's disease: results from DATATOP

Recent studies have suggested that higher serum cholesterol may be associated with lower occurrence of Parkinson's disease (PD). This study is to test the hypothesis that higher serum cholesterol correlates with slower PD progression. Baseline non-fasting serum total cholesterol was measured in...

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Veröffentlicht in:	PloS one 2011-08, Vol.6 (8), p.e22854
Hauptverfasser:	Huang, Xuemei, Auinger, Peggy, Eberly, Shirley, Oakes, David, Schwarzschild, Michael, Ascherio, Alberto, Mailman, Richard, Chen, Honglei
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of daily living Amyotrophic lateral sclerosis Analysis Antioxidants - therapeutic use Basal ganglia Biology Blood cholesterol Brain diseases Cardiovascular disease Central nervous system diseases Cholesterol Cholesterol - blood Cholesterol tests Clinical trials Confidence intervals Dentistry Departments Disease Progression Dopamine Endpoint Determination Epidemiology Evidence (Law) Fasting Female Females Humans Hypotheses L-dopa Laboratories Levodopa Male Males Medicine Middle Aged Movement disorders Neurodegenerative diseases Neurology Neurotoxicity Parkinson Disease - blood Parkinson Disease - drug therapy Parkinson Disease - pathology Parkinson's disease Proportional Hazards Models Randomized Controlled Trials as Topic Rodents Secondary analysis Selegiline Selegiline - therapeutic use Statins Studies Therapy Tocopherol Tocopherols Tocopherols - therapeutic use
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