Lgt processing is an essential step in Streptococcus suis lipoprotein mediated innate immune activation

Streptococcus suis causes invasive infections in pigs and occasionally in humans. The host innate immune system plays a major role in counteracting S. suis infections. The main components of S. suis able to activate the innate immune system likely include cell wall constituents that may be released...

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Veröffentlicht in:	PloS one 2011-07, Vol.6 (7), p.e22299
Hauptverfasser:	Wichgers, P.J, Rebel, J.M.J, Smits, M.A, Putten, J.P. van, Smith, H.E
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Animals Antibiotics Bacteria bacterial lipoproteins Biology Blood lipids Cell walls Cloning Cytokines Deactivation Enzyme Activation - drug effects Enzymes Gel electrophoresis Genetic aspects Health aspects HeLa Cells Hostages Humans identification Immune response Immune system Immunity Immunity, Innate - drug effects Immunity, Innate - immunology Immunology Inactivation Infection Infections Infectious diseases Innate immunity Interleukin 8 Laboratories Lactococcus lactis Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - microbiology lipid modification Lipoproteins Lipoproteins - metabolism Listeria Listeria monocytogenes Mass Spectrometry Mass spectroscopy Mutation - genetics Negotiation, mediation and arbitration Palmitic acid Penicillin Penicillins Penicillins - pharmacology Peripheral blood mononuclear cells pneumoniae polysaccharide prelipoproteins Protein Processing, Post-Translational - drug effects Proteins Scientific imaging serotype-2 Sodium lauryl sulfate Staphylococcus aureus Streptococcus Streptococcus infections Streptococcus pneumoniae Streptococcus suis - drug effects Streptococcus suis - enzymology Streptococcus suis - growth & development Suidae Sus scrofa Swine Toll-Like Receptors - metabolism Transcription Transferases - metabolism type-2 Veterinary Science virulence
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