Copy number variation in CNP267 region may be associated with hip bone size

Osteoporotic hip fracture (HF) is a serious global public health problem associated with high morbidity and mortality. Hip bone size (BS) has been identified as one of key measurable risk factors for HF, independent of bone mineral density (BMD). Hip BS is highly genetically determined, but genetic...

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Veröffentlicht in:	PloS one 2011-07, Vol.6 (7), p.e22035-e22035
Hauptverfasser:	Liu, Shan-Lin, Lei, Shu-Feng, Yang, Fang, Li, Xi, Liu, Rong, Nie, Shan, Liu, Xiao-Gang, Yang, Tie-Lin, Guo, Yan, Deng, Fei-Yan, Tian, Qing, Li, Jian, Liu, Yao-Zhong, Liu, Yong-Jun, Shen, Hui, Deng, Hong-Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Androgen receptors Asian Continental Ancestry Group - genetics Association analysis Biocompatibility Bioinformatics Biology Biomedical materials Bone and Bones - anatomy & histology Bone density Bone growth Bone mineral density Bone turnover Chromosome 2 Chromosomes, Human, Pair 2 - genetics Copy number Cultural differences Developmental biology DNA Copy Number Variations - genetics Education Ethnic Groups - genetics Ethnicity European Continental Ancestry Group - genetics Female FHL2 protein Fractures Gene expression Gene mapping Genes Genetic Association Studies Genetic diversity Genetic factors Genetics Genomes Genomics Health aspects Hip Hip - anatomy & histology Humans Insulin Insulin-like growth factor-binding protein 5 Laboratories Life sciences Male Males Medicine Metabolism Morbidity Mortality Mutation Organ Size - genetics Osteogenesis Osteoporosis Parkinson's disease Physiological aspects Polymorphism Protein binding Proteins Public health Risk analysis Risk factors Single-nucleotide polymorphism Trauma White people
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