Clusters of nucleotide substitutions and insertion/deletion mutations are associated with repeat sequences

The genome-sequencing gold rush has facilitated the use of comparative genomics to uncover patterns of genome evolution, although their causal mechanisms remain elusive. One such trend, ubiquitous to prokarya and eukarya, is the association of insertion/deletion mutations (indels) with increases in...

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Veröffentlicht in:PLoS biology 2011-06, Vol.9 (6), p.e1000622
Hauptverfasser: McDonald, Michael J, Wang, Wei-Chi, Huang, Hsien-Da, Leu, Jun-Yi
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Sprache:eng
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