Genome-wide association study for atopy and allergic rhinitis in a Singapore Chinese population

Allergic rhinitis (AR) is an atopic disease which affects about 600 million people worldwide and results from a complex interplay between genetic and environmental factors. However genetic association studies on known candidate genes yielded variable results. The aim of this study is to identify the...

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Veröffentlicht in:	PloS one 2011-05, Vol.6 (5), p.e19719-e19719
Hauptverfasser:	Andiappan, Anand Kumar, Wang, De Yun, Anantharaman, Ramani, Parate, Pallavi Nilkanth, Suri, Bani Kaur, Low, Hui Qi, Li, Yi, Zhao, Wanting, Castagnoli, Paola, Liu, Jianjun, Chew, Fook Tim
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Allergic rhinitis Allergies Asian People - genetics Asthma Atopy B cells Biology Case-Control Studies Chromosome 10 Chronic obstructive pulmonary disease Critical care Disease Environmental factors Female Genes Genetic diversity Genetic Predisposition to Disease Genetic research Genetic variance Genetics Genome-wide association studies Genome-Wide Association Study Genomes Genomics Histocompatibility antigen HLA HLA antigens Humans Hypersensitivity - epidemiology Hypersensitivity - genetics Hypotheses Hypoxia Immunology Male Medicine Pathogenesis Pathways Permeability Phenotype Polymorphism, Single Nucleotide - genetics Population Principal components analysis Quality control Replication Rhinitis Rhinitis - epidemiology Rhinitis - genetics Signal transduction Signaling Singapore - epidemiology Single-nucleotide polymorphism Studies Target recognition Young Adult
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