Association of short tandem repeat polymorphism in the promoter of prostate cancer antigen 3 gene with the risk of prostate cancer

PCA3 (prostate cancer antigen 3) gene is one of the most prostate cancer-specific genes at present. Consequently, the prostate-specific expression and the sharp up-regulation of PCA3 mRNA in prostate cancer suggest a unique transcriptional regulation, which possibly can be attributed to promoter pol...

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Veröffentlicht in:	PloS one 2011-05, Vol.6 (5), p.e20378-e20378
Hauptverfasser:	Zhou, Wu, Chen, Zhanguo, Hu, Wangqiang, Shen, Mo, Zhang, Xiaoxia, Li, Chengdi, Wen, Zhiliang, Wu, Xiuling, Hu, Yuanping, Zhang, Xiaohua, Duan, Xiuzhi, Han, Xiucui, Tao, Zhihua
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antigens Antigens, Neoplasm - genetics Biology Cancer Cancer genetics Chi-square test Chinese medicine Clinical outcomes Cloning Confidence intervals Deoxyribonucleic acid DNA DNA sequencing Gene expression Gene polymorphism Gene regulation Gene sequencing Genes Genetic aspects Genetic polymorphisms Genetic Predisposition to Disease Genotypes Health risk assessment Health risks Hospitals Humans Male Medical diagnosis Medical laboratories Medicine Messenger RNA Microsatellite Repeats - genetics Middle Aged Patients Peripheral blood Polymerase chain reaction Polymorphism Polymorphism, Genetic - genetics Promoter Regions, Genetic - genetics Prostate cancer Prostatic Neoplasms - epidemiology Prostatic Neoplasms - genetics Risk factors Statistical tests Transcription Trends Tumors Urine Urology
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