The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study

In the recently published meta-analysis of multiple sclerosis genome-wide association studies De Jager et al. identified three single nucleotide polymorphisms associated to MS: rs17824933 (CD6), rs1800693 (TNFRSF1A) and rs17445836 (61.5 kb from IRF8). To refine our understanding of these association...

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Veröffentlicht in:	PloS one 2011-04, Vol.6 (4), p.e18813-e18813
1. Verfasser:	International, Multiple Sclerosis Genetics Consortium
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antigens, CD - genetics Antigens, Differentiation, T-Lymphocyte - genetics Apoptosis Biology Case-Control Studies CD6 antigen Cell adhesion & migration Chromosomes Consortia Development and progression Etiology Gene mapping Genetic aspects Genetic research Genome-wide association studies Genomes Genomics Humans Independent sample Interferon Regulatory Factors - genetics Leukemia Loci Medicin och hälsovetenskap Medicine Meta-analysis Multiple sclerosis Multiple Sclerosis - genetics Mutation Pathogenesis Polymorphism, Single Nucleotide - genetics Ratios Receptors, Tumor Necrosis Factor, Type I - genetics Single nucleotide polymorphisms Single-nucleotide polymorphism Tumor necrosis factor-TNF
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