A volumetric method for quantifying atherosclerosis in mice by using microCT: comparison to en face

Precise quantification of atherosclerotic plaque in preclinical models of atherosclerosis requires the volumetric assessment of the lesion(s) while maintaining in situ architecture. Here we use micro-computed tomography (microCT) to detect ex vivo aortic plaque established in three dyslipidemic mous...

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Veröffentlicht in:	PloS one 2011-04, Vol.6 (4), p.e18800-e18800
Hauptverfasser:	Lloyd, David J, Helmering, Joan, Kaufman, Stephen A, Turk, James, Silva, Matt, Vasquez, Sergio, Weinstein, David, Johnston, Brad, Hale, Clarence, Véniant, Murielle M
Format:	Artikel
Sprache:	eng
Schlagworte:	Angioplasty Animal models Animals Aorta Aorta, Thoracic - diagnostic imaging Aorta, Thoracic - pathology Apolipoproteins Arteriosclerosis Atherosclerosis Atherosclerosis - diagnostic imaging Atherosclerosis - pathology CAT scans Cholesterol Computed tomography Computer graphics Coronary vessels Diet Disease Models, Animal Face Heart Histology Histopathology Laboratories Lesions Lipids Low density lipoprotein receptors Low density lipoproteins Male Medical imaging Medicine Metabolic disorders Metabolic syndrome Methods Mice Mice, Knockout NMR Nuclear magnetic resonance Occlusion Receptor density Reproducibility of Results Rodents Signal processing Surface area Technology Technology application Thorax Tomography, X-Ray Computed - methods Veins & arteries
Online-Zugang:	Volltext
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